There is no sexual content, though there is a brief scene where a character is seen with an exposed back while receiving medical treatment. The film focuses entirely on themes of nature and conflict rather than romance or nudity.

This film features frequent, intense battle sequences with realistic depictions of injuries, including severed limbs and blood splatter. The stylized nature of the animation does not mitigate the graphic and often disturbing nature of the combat.

The dialogue is very clean, containing only very mild exclamations like "d*mn" used in the heat of conflict. These instances occur infrequently and are used solely to emphasize the intensity of the characters' situations.

Characters are occasionally seen drinking sake in social tavern settings and others are shown smoking tobacco via pipes. These habits reflect the historical setting of the film and are not a central focus of the narrative.

The film contains many ominous and disturbing images, including grotesque, writhing demon creatures and decay. Younger viewers may find the overall tone, which deals with death and environmental destruction, quite stressful and dark.

Promotes the necessity of compromise over conflict, the virtues of empathy, and the importance of ecological stewardship.

Ashitaka demonstrates courage, integrity, and diplomatic grace; San exhibits fierce independence and dedication to her convictions.

Features distinct cultural groups with unique traditions and values, emphasizing agency and the complexity of conflicting societal survival strategies.

Encourages critical thinking regarding human impact on ecosystems, the nature of greed, and the evolution of social responsibilities.